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8-Aug-14 9:30 AM  CST  

Antipsychotic Medication Linked To Less Brain Volume 

Aging is usually never an easy process for most individuals. Atrophy, losses in brain cells and volume can happen in a patients 30’s and continue into old age.  Researchers from the University of Oulu, Finland, and the University of Cambridge have conducted recent studies on brain volume and the difference between people that are healthy without any emotional problems to those who are completely free of these problems. Researchers have discovered some interesting points. The study can be fully read by going to the open access journal PLOS ONE.  Here is a look at some points from the study: 


  • Medications. Recent studies show that antipsychotic drugs may lead to decreases in brain volume. These are generally medications used to treat schizophrenia. 


  • Dosages. Researchers found that the higher the dose of the schizophrenia drug, the higher the loss in brain volume. 


  • Symptoms. Researchers were not able to identify if the amount or effect of brain volume loss had any impact on the patients cognitive functioning. 


            Dr. Juha Vejola, from the Department of Psychiatry at the University of Oulu, recently commented on her team’s findings. “We all lose some brain tissue as we get older, but people with schizophrenia lose it at a faster rate. We’ve shown that this loss seems to be linked to the antipsychotic medication people are taking,” said Vejola. 

To read more drug news of interest to pharmacy technicians, please visit






1. Baulkman, J. “Antipsychotic Medication Linked To Slight Decrease In Brain Volume.” University Herald. Web. Date of Access: 3 Aug 2014.

2. Drug Discovery & Development Reports. “Antipsychotic Drugs Linked To Decreased Brain Volume.” Drug Discovery & Development. Web. Date of Access: 3 Aug 2014.

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Source: Jennifer S. O’Reilly

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